Fluconazole 800mg daily
UseofHigh-Dose Fluconazole as Salvage Therapyfor Cryptococcal Meningitis in Patients withAIDS was discontinued and he was placed on mg of oral fluconazole daily.
It is well absorbed and passes readily across the blood-brain barrier into the cerebrospinal fluid. It is slowly eliminated unchanged in the urine, fluconazole 800mg daily.
High-dose therapy with fluconazole > or = 800 mg day-1.
Cryptococcal meningitis Following treatment with amphotericin B For either two weeks or until the condition has stabilised or improved: Oesophageal and daily oropharyngeal candidiasis mg as an initial loading dose followed by mg daily until fluconazole have resolved. Doses of up to mg daily have been used in very resistant 800mg. Vaginal candidiasis mg as a single oral dose.
Coccidioidomycosis mg orally or intravenously daily in patients unable to tolerate amphotericin B. Contraindications Hypersensitivity to azole derivatives.
Precautions Dosage fluconazole be daily in 800mg with the creatinine clearance rate in patients with renal impairment. Use in pregnancy Safe use in pregnancy has not been established. The need for treatment must be determined by the condition of the mother, fluconazole 800mg daily.
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Adverse effects Fluconazole is generally well-tolerated. Nausea is the most frequently reported adverse effect.
Fluconazole Dosage
Vomiting and abdominal distension and discomfort are also reported. Elevation of hepatic enzyme levels, fluconazole 800mg daily, which occurs in a small percentage of individuals, is readily reversible in the early stages. Treatment should be discontinued if signs develop that are suggestive of hepatic disease.
Exfoliative skin disorders have been reported, but a casual association has not been established. Drug interactions Concomitant administration of terfenadine, astemizole or cisapride should be avoided as potentially fatal cardiac irregularities including prolonged Q-T intervals and ventricular fibrillation may occur.
The hepatic metabolism of lipid soluble drugs such as ciclosporin, phenytoin, sulfonylureas, warfarin and rarely theophylline is inhibited.
Fluconazole 200mg Capsules
Rifampicin and rifabutin 800mg the clearance of fluconazole, the dose of fluconazole should be increased by one half to allow for this. Overdosage No experience has been gained with overdosage of fluconazole. Induction of emesis and gastric lavage may be tried in the case of accidental overdosage. Storage Tablets should be daily in well-closed containers, protected from light. Intravenous preparations fluconazole be stored in well-closed containers and should not be allowed to freeze.